CRISPR/Cas9 Mutagenesis in Phlebotomus papatasi: the Immune Deficiency Pathway Impacts Vector Competence for Leishmania major

ABSTRACT Sand flies are the natural vectors for the Leishmania species that produce a spectrum of diseases in their mammalian hosts, including humans.Studies of sand fly/Leishmania interactions have been limited read more by the absence of genome editing techniques applicable to these insects.In this report, we adapted CRISPR (clustered regularly i

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A Refined Self-Tuning Filter-Based Instantaneous Power Theory Algorithm for Indirect Current Controlled Three-Level Inverter-Based Shunt Active Power Filters under Non-sinusoidal Source Voltage Conditions

In this paper, a refined reference current generation algorithm based on instantaneous power (pq) theory is proposed, for operation of an indirect current controlled (ICC) three-level neutral-point diode clamped (NPC) inverter-based shunt active power filter (SAPF) under non-sinusoidal source voltage conditions.SAPF is recognized as one of the most

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